Commentary: long-term lubiprostone for constipation predominant IBS
نویسندگان
چکیده
منابع مشابه
Chronic Constipation and Constipation-Predominant IBS: Separate and Distinct Disorders or a Spectrum of Disease?
Rome III diagnostic criteria separate patients with idiopathic chronic constipation into mutually exclusive categories of constipation-predominant irritable bowel syndrome (IBS-C) or functional constipation (FC). However, several experts think that these conditions are not different disorders, but parts of a continuum. To shed light on this issue, we examined studies that compared IBS-C with FC...
متن کاملLubiprostone: a novel treatment for chronic constipation
Chronic constipation is highly prevalent, reduces patients' quality of life, and imposes a significant health care burden on society. Lifestyle modifications and over-the-counter agents improve symptoms of constipation in some patients, however many patients have persistent symptoms and require the use of prescription medications. Three prescription medications are currently Food and Drug Admin...
متن کاملBurden of constipation-predominant irritable bowel syndrome (IBS-C) in France, Italy, and the United Kingdom
BACKGROUND Several studies have examined the effect of irritable bowel syndrome (IBS) on health outcomes in Western Europe, but less research has focused on the constipation subtype (IBS-C). The current study addresses this gap by comparing patients with IBS-C and matched controls for health status, work productivity, and resource utilization. METHODS Data were obtained from the 2010 5EU Nati...
متن کاملLubiprostone: evaluation of the newest medication for the treatment of adult women with constipation-predominant irritable bowel syndrome
Irritable bowel syndrome (IBS) is a chronic disorder that affects primarily female patients and is thought also to afflict approximately 7%-10% of the population of the Western World. Although bowel habits may change over the course of years, patients with IBS are characterized according to their predominant bowel habit, constipation (IBS-C), diarrhea (IBS-D), or mixed type (IBS-M), and treatme...
متن کاملLubiprostone for the treatment of functional constipation in children.
OBJECTIVES Pediatric functional constipation is common; effective, easily administered treatment options are limited. Lubiprostone is an oral chloride channel protein-2 activator that stimulates gastrointestinal fluid secretion, softens stools, and facilitates bowel movements (BMs). We evaluated the safety and effectiveness of lubiprostone in children and adolescents with functional constipatio...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2012
ISSN: 0269-2813
DOI: 10.1111/j.1365-2036.2012.05041.x